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LCT 0.023   Last updated EOD 23rd April 2018
Fact sheet
The following fact sheets provide a summary of our current business and research pipeline.
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Fact sheet

The following fact sheet provides a summary of our current business and research pipeline.

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Cell therapy for neurodegenerative diseases

Living Cell Technologies Limited (LCT) is an Australasian biotechnology company improving the wellbeing of people with serious diseases worldwide by discovering, developing and commercialising regenerative treatments which restore function using naturally occurring cells.

 

Our lead product, NTCELL®, is an alginate coated capsule containing clusters of neonatal porcine choroid plexus cells. After transplantation NTCELL functions as a biological factory, producing factors to promote new central nervous system growth and repair disease-induced nerve degeneration.

 

The Phase I/IIa clinical trial of NTCELL for the treatment of Parkinson’s disease, in New Zealand, met the primary endpoint of safety and in the three-year follow-up showed persistent long-term improvement in some patients. Results from this trial were used to design a larger Phase IIb trial to confirm the most effective dose of NTCELL, define any placebo component of the response and further identify the initial target Parkinson’s disease patient sub group. This trial commenced in March 2016. The 26-week results of this trial required further analysis and patients will continue to be monitored in accordance with the study extension protocol. One year follow-up data in patients from all three groups of this trial will be announced in May 2018.

 

In addition to Parkinson’s disease, NTCELL has the potential to be used in a number of other central nervous system indications, including Huntington’s, Alzheimer’s and motor neurone diseases including amyotrophic lateral sclerosis (ALS).

 

LCT’s proprietary encapsulation technology, IMMUPEL™, allows cell therapies to be used without the need for co-treatment with drugs that suppress the immune system.

 

LCT is listed on the Australian (ASX: LCT) and US (OTCQX: LVCLY) stock exchanges and is incorporated in Australia, with operations based in New Zealand.

— 11 April 2018

LCT Strategy Update

Since the AGM, LCT’s Board and management have been working diligently, focused on developing a robust, well-considered and comprehensive strategy; one that makes the best use of our expertise, proprietary assets, partnerships and available funds to give shareholders the best chance of achieving a return on your investment. This is an outline of that strategy.

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— 22 February 2018

Half yearly report ended 31 December 2017

In the half yearly report for the six months ended 31 December 2017 the consolidated operating loss after income tax for the period 1 July to 31 December 2017 was $1.8m (2016 loss $2.1 m). The main reason for the decreased loss is that during the period, no patients in the Phase IIb clinical trial of NTCELL® for Parkinson’s disease were treated and no NTCELL was produced.

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— 16 September 2017

Sir Richard Faull on RNZ National

On Saturday Morning on RNZ National, LCT Scientific Advisor Sir Richard Faull and businessman Bernie Crosby talk to Kim Hill about the work of the University of Auckland Centre for Brain Research and finding a cure for Parkinson's disease.

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— 13 June 2017

Pig brain cells implanted into brains of people with Parkinson’s

Would you have pig cells implanted in your brain? Some people with Parkinson’s disease have, in the hope it will stop their disease progressing. The approach is still in the early stages of testing, but initial results from four people look promising, with all showing some improvement 18 months after surgery. Living Cell Technologies, based in Auckland, New Zealand, has been developing a treatment that uses cells from the choroid plexus in pigs. This brain structure makes a cocktail of growth factors and signalling molecules known to help keep nerve cells healthy.

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There are no forthcoming events at present.

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Announcements

— 11 April 2018

LCT Strategy Update

Since the AGM, LCT’s Board and management have been working diligently, focused on developing a robust, well-considered and comprehensive strategy; one that makes the best use of our expertise, proprietary assets, partnerships and available funds to give shareholders the best chance of achieving a return on your investment. This is an outline of that strategy.

Read More Read Less

— 22 February 2018

Half yearly report ended 31 December 2017

In the half yearly report for the six months ended 31 December 2017 the consolidated operating loss after income tax for the period 1 July to 31 December 2017 was $1.8m (2016 loss $2.1 m). The main reason for the decreased loss is that during the period, no patients in the Phase IIb clinical trial of NTCELL® for Parkinson’s disease were treated and no NTCELL was produced.

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LCT in the News

— 16 September 2017

Sir Richard Faull on RNZ National

On Saturday Morning on RNZ National, LCT Scientific Advisor Sir Richard Faull and businessman Bernie Crosby talk to Kim Hill about the work of the University of Auckland Centre for Brain Research and finding a cure for Parkinson's disease.

Read More Read Less

— 13 June 2017

Pig brain cells implanted into brains of people with Parkinson’s

Would you have pig cells implanted in your brain? Some people with Parkinson’s disease have, in the hope it will stop their disease progressing. The approach is still in the early stages of testing, but initial results from four people look promising, with all showing some improvement 18 months after surgery. Living Cell Technologies, based in Auckland, New Zealand, has been developing a treatment that uses cells from the choroid plexus in pigs. This brain structure makes a cocktail of growth factors and signalling molecules known to help keep nerve cells healthy.

Read More Read Less
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Events
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There are no forthcoming events at present.

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